The expense associated with Tumor-Infiltrating Lymphocyte (TIL) therapy for melanoma varies based on factors like geographic location and the healthcare facility offering the treatment. Specifically, in the United States, the cost for TIL therapy can range substantially, starting from around $250,000 and potentially escalating to $750,000. In contrast, Sheba Medical Center in Israel, known for providing this advanced melanoma treatment, offers it at a more competitive rate of $120,000 USD.

The quoted figures typically cover various components of the treatment process, including the extraction and cultivation of the TILs, the infusion process, and any necessary supportive care. It's crucial to remember that these costs are subject to change based on the specific needs of the patient, the treatment's complexity, and other relevant medical considerations.


Sheba Medical Center has been at the forefront of TIL (Tumor-Infiltrating Lymphocyte) therapy for melanoma since its early development in 2017. The hospital's innovative approach began with extensive research and clinical trials aimed at harnessing the body's immune system to fight cancer. Sheba’s TIL program was established under the leadership of Dr. Jacob Schachter and Dr. Michal Lotem, who have been pivotal in advancing this groundbreaking treatment. Over the years, Sheba has refined the process, significantly improving patient outcomes and positioning itself as a leading center for TIL therapy worldwide.


How to Check if TIL Treatment is Suitable for You

To determine if TIL therapy is appropriate for you, please send us the following documents:

  1. A medical summary in English from your treating oncologist, in chronological order, with a date from the last month.
  2. The report of your most recent brain MRI in English.
  3. The report of your most recent PET scan in English.

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